Stemrd/JAGG-1 Fc融合，人/1000µg/JAGGFC-1000
商品编号：
JAGGFC-1000
品牌：
Stemrd
市场价：
¥59620.00
美元价：
29810.00
产品分类：
破碎混匀
公司分类：
Crushing_blending
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Source | human 293 cells | M.W. | ~180 kDa | CAS No. | |
|---|---|---|---|---|---|
| Structural Info | |||||
| Formulation | Lyophilized in a sterile solution of PBS. | ||||
| Reconstitution | Before reconstitution, werecommend a brief spin to drive down any material dislodged from the bottom ofthe tube. The lyophilized peptide shouldbe reconstituted in sterile water. | ||||
| Stability | The lyophilized protein isstable for at least 1 year if stored at -80°C. Reconstituted protein is stable for at least 1 month at 4 °C, but shouldbe stored in aliquots at -80°C for longer term. Avoid repeated freeze andthaw. | ||||
| Purity | Greater than 90% as determined by SDS-PAGE analysis | ||||
| Biological Activity | Determined by a Notch pathway specific reporter gene assay.EC50s are in the range of 200 – 1000 ng/mL. | ||||
| Country of Origin | USA | ||||
The Notch pathwayis an important pathway in stem cell functions.Jagged-1, a ligand for Notch receptors, is a 180kDa type 1 membraneglycoprotein of the Delta/Serrate/Lag2 (DSL) family.StemRD’s Jagged-1 Fcfusion protein is expressed in human 293 cells as the 1046aa N-terminalextracellular domain of Jagged-1 fused to the Fc domain of human IgG1. This fusion stabilizes Jagged-1 in vitro andin vivo without significant compromise in its biological activity.
Product Sheet
品牌介绍
stemRD及其合作伙伴已经开发出一种高效的方法，可以在人细胞系中表达生物活性重组蛋白。由于这些细胞在无血清，无蛋白质和化学成分明确的培养基中生长，因此通过此过程制得的产品不含异种，并且具有人类特异性的转录后修饰，例如糖基化。使用该系统，我们已经能够生产出许多对干细胞的生长和分化至关重要的生物活性蛋白。
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