Stemrd/SAG/25 mg/SAG-025
市场价：
¥26980.00
美元价：
13490.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Source | M.W. | 599 | CAS No. | 364590-63-6 | |
|---|---|---|---|---|---|
| Structural Info | C28H28ClN3OS·2HCl·2H2O | ||||
| Formulation | Solution. 2.5 mg/mL in DMSO (4 mM) | ||||
| Reconstitution | The compound has been dissolved in DMSO. | ||||
| Stability | The powder is stable for at least 2 year if stored at-20 °C.The dissolved compound isstable for at least 1 month at 4 °C, but should be stored in aliquots at-20 °C for longer term. Protectfrom light. | ||||
| Purity | Greater than 98% as determined by LC/MS analysis.LC/MS and/or NMR data available upon request. | ||||
| Biological Activity | In a cell-based assay measuring the activation of the Gli-1 reporter gene, this compound gives EC50 of 2-10 nM. | ||||
| Country of Origin | |||||
SAG is a highly potent agonist of SMO (smoothened). This small molecule compound activates thehedgehog pathway by directly binding to SMO. Note: in the Gli-1 reporter gene assay, SAG acts as an activator atconcentrations from approximately 1 nM to 1 uM, but as an inhibitor atconcentrations high than 1 uM.Ref: Chen, J.K., et al. 2002. Proc. Natl. Acad. Sci. USA99, 14071
Product Sheet
品牌介绍
stemRD及其合作伙伴已经开发出一种高效的方法，可以在人细胞系中表达生物活性重组蛋白。由于这些细胞在无血清，无蛋白质和化学成分明确的培养基中生长，因此通过此过程制得的产品不含异种，并且具有人类特异性的转录后修饰，例如糖基化。使用该系统，我们已经能够生产出许多对干细胞的生长和分化至关重要的生物活性蛋白。
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